A research team at POSTECH has developed an innovative injectable adhesive hydrogel for bone regeneration. This hydrogel uses harmless visible light to enable crosslinking and mineralization, eliminating the need for bone grafts. The hydrogel precursor is made from a combination of alginate, mussel adhesive protein with an RGD peptide, calcium ions, phosphonodiols, and a photoinitiator. Its coacervate-based formulation, which is water-immiscible, ensures the hydrogel maintains its shape and position after injection into the body.
Next-generation hydrogel: A game-changer in bone regeneration
With harmless visible light.
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