Researchers from Chiba University, Japan, used fruit flies to explore how high-fat diets (HFDs) affect memory and brain health. They found that HFDs disrupt autophagy, the brain’s cellular recycling system, leading to impaired intermediate and long-term memory. However, short-term memory remained unaffected.
HFD-fed flies showed signs of autophagic dysfunction and altered glucose and lipid metabolism. Memory tests revealed that HFD mainly affected intermediate and long-term memory.
