Uncovering mechanisms behind severe COVID-19

A study by researchers from Weill Cornell Medicine, Johns Hopkins Medicine, Children’s Hospital of Philadelphia, the University of Pittsburgh, and other members of the COVID-19 International Research Team suggests that severe COVID-19 may be linked to the SARS-CoV-2 virus’s effect on mitochondria. Using RNA sequencing and other lab techniques on patient and animal model tissue samples, the researchers uncovered key molecular pathways involved in this process, shedding new light on the mechanisms driving severe COVID-19.