A protein that balances DNA replication and restarting identified

It balance nuclease and helicase activity.

A study by Professor Jo Morris from the University of Birmingham has identified a protein called USP50, which is essential for DNA replication. USP50 helps select the appropriate nucleases and helicases—enzymes that cut or unwind DNA—especially when the replication process faces challenges and needs to restart. This discovery highlights the protein’s crucial role in ensuring proper DNA replication.

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