Excessive fat buildup in the liver, or fatty liver disease, can lead to serious metabolic disorders. While much research has focused on fat processing in the liver, recent studies emphasize the gut’s important role.
A new study from Fujita Health University investigates how proglucagon-derived peptides (PGDPs) affect fat absorption and liver fat accumulation. Researchers used genetically modified mice that lack PGDPs (GCGKO mice) to observe their response to a high-fat diet (HFD) over seven days.