Friday, February 7, 2025

DNA Microbeads Enable Creation of Complex Organoids

Controlling the development of cultivated tissue

The interdisciplinary research team of biologists, physicians, physicists, and materials scientists developed a new molecular engineering technique that uses DNA microbeads to control the development of cultivated tissue. DNA microbeads release growth factors or signals inside tissue structures, creating more complex organoids that better mimic actual tissues and have a more realistic mix of cells.

These DNA microbeads can be “loaded” with proteins or other molecules. They are injected into the organoids and release their cargo when exposed to UV light.

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